• Adavosertib monotherapy active in recurrent uterine serous carcinoma

    3 days ago - By Healio

    Adavosertib demonstrated clinical activity among women with recurrent uterine serous carcinoma, according to results of a phase 2 study published in Journal of Clinical Oncology.
    “Uterine serous carcinoma is a distinct histologic subtype of endometrial cancer that accounts for up to 40% of endometrial cancer deaths and for which effective therapies are limited,” Joyce F. Liu, MD, MPH, researcher in the department of medical oncology at Dana-Farber Cancer Institute, and colleagues wrote. “Molecular characterization of uterine serous carcinoma suggests the presence of
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  • Linzagolix effective in women with uterine fibroids

    Linzagolix effective in women with uterine fibroids

    3 days ago - By Healio

    Linzagolix reduced uterine and fibroid volumes and improved pain and hemoglobin levels in women with uterine fibroids, according to multiple analyses of two phase 3 clinical trials.
    The findings were presented at the American College of Obstetricians and Gynecologists Annual Clinical and Scientific Meeting.
    “There are currently no long-term medical therapies for uterine fibroids,” William H. Catherino, MD, PhD, chair and professor in the research division of the School of Medicine at the Uniformed Services University of the Health Sciences in Bethesda, Maryland, said during a
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