• Recognition, Evaluation, and Management of Pediatric Hereditary Angioedema

    1 month ago - By Pediatric Emergency Care

    No abstract available
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  • Recognition, Evaluation, and Management of Pediatric Hereditary Angioedema

    Recognition, Evaluation, and Management of Pediatric Hereditary Angioedema

    1 month ago - By Pediatric Emergency Care

    Hereditary angioedema is a rare, often underrecognized genetic disorder caused by either a C1 esterase inhibitor deficiency or mutation. This leads to overproduction of bradykinin resulting in vasodilation, vascular leakage, and transient nonpitting angioedema occurring most frequently in the face, neck, upper airway, abdomen, and/or extremities. Involvement of the tongue and laryngopharynx has been associated with asphyxiation and death. Hereditary angioedema is an autosomal-dominant condition; therefore, there is a 50% chance an offspring will inherit this disorder. Any patient...
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