The ingredients and science behind growth factor-based topicals.By Inga Hansen Growth factor-BASED serums and creams have become ubiquitous in topical antiaging skin care. But what these different products contain can vary widely. Some products contain actual growth factors-either animal- or plant-derived-and others use so-called “signaling” ingredients, typically peptides that trigger the cells in a manner similar to naturally occurring growth factors. In all cases, the goal is to combat the changes that occur in aging skin
“When the body is working normally, growth factors in the skin signal the fibroblasts to make collagen or elastin, for example, while matrix metalloproteinases , such as collagenase and elastinase, remove damaged cells and proteins,” says Robert Manzo, founder and chemist with skincare manufacturer Skinprint. “As we age, our growth factors decrease but our MMPs stay where they are, so they start to degrade healthy tissue. Hence people started to put growth factors into their...
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