• Molecular hallmarks of tumor hypoxia across 19 cancer types discovered

    2 monthes ago - By News Medical

    Unlike healthy tissues, tumors thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despite being a well-known cause of therapy resistance and metastasis, the impact of low oxygen, known as hypoxia, on tumor cells is poorly understood.
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  • Scientists discover mutational signatures of tumor hypoxia

    2 monthes ago - By News Medical

    Researchers have discovered mutational signatures of tumor hypoxia in 19 cancer types that could be used to identify patients who need higher treatment doses.
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