• Novel therapy inhibits complement to preserve neurons and reduce inflammation after stroke

    10 monthes ago - By ScienceDaily

    Researchers report that, after ischemic stroke, the complement system identifies stressed but salvageable neurons for removal by microglial phagocytosis. To preserve these neurons, the investigators designed a novel therapeutic that targets a complement inhibitor to a damage signal expressed after stroke. A single post-stroke injection protected neurons from microglial attack in a preclinical model, reducing neuronal loss.
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