• Epigallocatechin Gallate Has a Neurorescue Effect in a Mouse Model of Parkinson Disease

    1 month ago - By Nutrition

    Background: Parkinson disease is a neurodegenerative disorder that has been associated with many factors, including oxidative stress, inflammation, and iron accumulation. The antioxidant, anti-inflammatory, and iron-chelating properties of epigallocatechin gallate , a major polyphenol in green tea, may offer protection against PD. Objective: We sought to determine the neurorescue effects of EGCG and the role of iron in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine -induced PD. Methods: We evaluated the neurorescue effect of EGCG against MPTP-induced neurodegeneration in C57 male black mice...
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