• Clinical trial shows anti-tumor responses in metastatic castration-resistant prostate cancer patients

    1 month ago - By News Medical

    The preliminary results of a Phase I clinical trial conducted by researchers at the Yale Cancer Center have shown that ARV-110, an androgen receptor PROTAC protein degrader, demonstrates clinical evidence of anti-tumor responses in patients with metastatic castration-resistant prostate cancer who have failed prior therapy.
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  • Addition of monoclonal antibody to trimodality therapy offers no benefit in HER2 over expressing esophageal cancer

    1 month ago - By News Medical

    Results of the NRG Oncology clinical trial RTOG 1010 indicated that the addition of the monoclonal antibody trastuzumab to neoadjuvant trimodality treatment did not improve disease-free survival outcomes for patient with HER2 overexpressing local and locally advanced esophageal adenocarcinoma.
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  • Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

    1 month ago - By News Medical

    A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.
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