• Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: a randomized controlled trial

    1 month ago - By American Journal of Clinical Nutrition

    ABSTRACTBackgroundWeight loss is critical for preventing and managing obesity-related diseases. There is a notable lack of valid and reliable means to manage patients with overweight/obesity and knee osteoarthritis .ObjectiveTo determine the efficacy and safety of liraglutide in a 30 mg/d dosing in patients with overweight/obesity and KOA.MethodsThe trial was designed as a randomized controlled trial including patients between the age of 18 and 74 y with KOA and a BMI ≥27 .Patients underwent a pre-random assignment diet intervention. At week 0, patients having lost > 5% of their body...
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