• Infant Formula Feeding Increases Hepatic Cholesterol 7α Hydroxylase Expression and Fecal Bile Acid Loss in Neonatal Piglets

    4 monthes ago - By Journal of Nutrition

    AbstractBackgroundDuring the postnatal feeding period, formula-fed infants have higher cholesterol synthesis rates and lower circulating cholesterol concentrations than their breastfed counterparts. Although this disparity has been attributed to the uniformly low dietary cholesterol content of typical infant formulas, little is known of the underlying mechanisms associated with this altered cholesterol metabolism phenotype.ObjectiveWe aimed to determine the molecular etiology of diet-associated changes in early-life cholesterol metabolism with the use of a postnatal piglet feeding...
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