• Prebiotics in irritable bowel syndrome and other functional bowel disorders in adults: a systematic review and meta-analysis of randomized controlled trials

    2 monthes ago - By American Journal of Clinical Nutrition

    ABSTRACTBackgroundIrritable bowel syndrome and other functional bowel disorders are prevalent disorders with altered microbiota. Prebiotics positively augment gut microbiota and may offer therapeutic potential.ObjectivesThe aim of this study was to investigate the effect of prebiotics compared with placebo on global response, gastrointestinal symptoms, quality of life , and gut microbiota, via systematic review and meta-analysis of randomized controlled trials in adults with IBS and other FBDs.MethodsStudies were identified using electronic databases, back-searching reference lists, and...
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  • Β-Hydroxy-β-methylbutyrate and its impact on skeletal muscle mass and physical function in clinical practice: a systematic review and meta-analysis

    2 monthes ago - By American Journal of Clinical Nutrition

    ABSTRACTBackgroundLoss of skeletal muscle mass and muscle weakness are common in a variety of clinical conditions with both wasting and weakness associated with an impairment of physical function. β-Hydroxy-β-methylbutyrate is a nutrition supplement that has been shown to favorably influence muscle protein turnover and thus potentially plays a role in ameliorating skeletal muscle wasting and weakness.ObjectivesThe aim of this study was to investigate the efficacy of HMB alone, or supplements containing HMB, on skeletal muscle mass and physical function in a variety of clinical conditions...
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