• Ticagrelor bests clopidogrel for suppressing high platelet reactivity after TAVR

    5 monthes ago - By Healio

    Ticagrelor plus aspirin, when compared with clopidogrel plus aspirin, resulted in faster and more sustained suppression of high platelet reactivity in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, according to the REAC-TAVI trial.
    The study enrolled patients with severe aortic stenosis undergoing TAVR from November 2015 to May 2017 at seven centers in Spain. All patients were on aspirin 100 mg daily and needed to be on clopidogrel maintenance dosing of 75 mg daily for at least 4 days before TAVR, and those who were not on clopidogrel were pretreated
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