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Master Doctor Search: Myeloma
Myeloma Drug's Eye Toxicity Faces FDA Scrutiny
WASHINGTON - The regulatory fate of a new multiple myeloma drug could hinge on a novel ocular toxicity uncommon among other therapies for the disease. During a virtual meeting...
1 day ago - MedPage Today
Death Halts 'Off-the-Shelf' CAR-T Trial; BP and CRC; Obesity Dulls Docetaxel?
FDA placed a clinical hold on the phase I MELANI-01 trial of UCARTCS1A - an investigational "off-the-shelf" CAR T-cell therapy - after a multiple myeloma patient died from...
5 days ago - MedPageToday
PI Makes Case as Maintenance for Nontransplant Myeloma
Transplant-ineligible patients with newly diagnosed multiple myeloma lived almost twice as long without disease progression with ixazomib maintenance therapy, results of a...
19 days ago - MedPageToday
New Standard for Relapsed/Refractory Multiple Myeloma?
Isatuximab added to carfilzomib and dexamethasone extended progression-free survival compared with carfilzomib and dexamethasone alone in patients with relapsed/refractory...
29 days ago - MedPageToday
Newly Diagnosed MM: RVd Still Standard of Care
The combination of the next-generation proteasome inhibitor carfilzomib, lenalidomide, and dexamethasone did not demonstrate superior progression-free survival in newly...
1 month ago - MedPageToday
High Marks for CAR T Cells in R/R Myeloma
Three-fourths of patients with heavily treated multiple myeloma responded to chimeric antigen receptor T-cell therapy targeting B-cell maturation antigen , results of a pivotal...
1 month ago - MedPageToday
VRd Still Reigns in Newly Diagnosed Myeloma
]]> - The combination of bortezomib , lenalidomide , and dexamethasone, or VRd, successfully fended off a direct challenge to its position as standard of care in newly...
1 month ago - MedPageToday
Add-On Selinexor Boosts PFS in Pretreated Myeloma
]]> - Including the XPO1 inhibitor selinexor in a weekly bortezomib regimen improved oncologic outcomes and reduced rates of neuropathy in relapsed or refractory multiple...
1 month ago - MedPageToday
New tool may help predict the best treatment for multiple myeloma
In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple...
1 month ago - News Medical - 2 articles
Combination therapy does not show superior efficacy in newly diagnosed myeloma
The combination of carfilzomib, lenalidomide, and dexamethasone did not show superior efficacy in patients with newly diagnosed myeloma absent a high-risk disease prognosis...
1 month ago - News Medical - 2 articles
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MRNA Vax Against COVID-19 Passes First Hurdle
Moderna's mRNA vaccine against SARS-CoV-2 produced an immune response in healthy adult volunteers and was mostly well-tolerated, interim findings from a phase I dose-escalation...
Why Obesity May Stack the Deck for COVID-19 Risk
It has become clearer that people who are obese are one of the groups at highest risk from the disease, regardless of their age
25 Mental Health Apps, Directories, and Podcasts to Help Improve Black...
Focusing on your mental health is an important aspect to well-being, but due to the stigma surrounding mental health, many people are afraid or embarrassed to discuss what...
Bacteria in newborn's stool may indicate risk of obesity
The bacteria found in a baby's first stool can predict its likelihood of becoming overweight by the age of three, according to a new prospective, populationâbased study...
Nitrates in amaranth boost aerobic performance, study finds
An extract of amaranth was shown to boost the aerobic capacity of young male subjects in a cycling test, a study has found.
Study Reports Raise in HIV, TB, Malaria Deaths Due to COVID-19 Pandemic
Prioritising the most critical services, like antiretroviral therapy for HIV, timely TB diagnosis and treatment, and provision of long-lasting insecticide-treated nets for...
Half of covid-positive nursing home residents had no symptoms
A Johns Hopkins University study urges universal coronavirus testing in long-term care homes after 55% of 354 patients had no symptoms at the time the tested positive for the...
If You Only Have One Exercise In Your Routine, Make It One Of These
Fitness pros share the workouts and moves they would do every day if they could.
Andexxa Enters Guidelines for Bleeding on Oral Anticoagulation
Recently-approved treatments prompted an update to American College of Cardiology guidance on managing bleeding in patients on oral anticoagulation. New guidance included the...
In-app Mental Health Support By Snapchat in India
Snapchat has announced in-app support to its users in India who may be experiencing a mental health or emotional crisis.