• Genetic variation may affect efficacy of short-term antipsychotics

    4 monthes ago - By Healio

    Using whole-exome and targeted sequencing, researchers found that damaging variants on two gene sets may affect the efficacy of short-term antipsychotic medications.
    “Systematic search for common variants influencing antipsychotic drug response by genome-wide association study so far has been unsuccessful,” Qiang Wang, MD, PhD, from the Mental Health Center and Psychiatric Laboratory, West China Hospital of Sichuan University, and colleagues wrote in JAMA Psychiatry. “The heritability of antipsychotic drug response is not easy to quantify because the phenotype can be assessed
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