• Researchers generate stable cartilage tissue from adult mesenchymal stem cells

    One year ago - By News Medical

    Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
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  • At Issue: Stem cell therapy

    One year ago - By Healio

    Articular cartilage stands to benefit the most from stem cell therapy. While stem cells have been identified in nearly every human tissue, articular cartilage contains few regenerative cells. Cartilage is avascular and is devoid of a perivascular stem cell population, so when injury occurs, there is little response from the cartilage tissue itself. Migrating synovial cells may contribute to the body's often-inadequate healing response.
    Although it is widely believed progenitor cells act mainly via paracrine signaling to control the local tissue environment, articular cartilage
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