• Researchers identify long-sought activator of sigma receptors in human cells

    5 monthes ago - By ScienceDaily

    Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive. Now, researchers show that choline is an endogenous activator of sigma-1 receptors.
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  • Scientists identify endogenous activator of sigma-1 receptors in human cells

    5 monthes ago - By News Medical

    Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive.
    Read more ...