• High-dose edoxaban safety favorability vs. warfarin greater in women than men

    9 days ago - By Healio

    Among women with atrial fibrillation at elevated CV risk, treatment with high-dose edoxaban vs. warfarin conferred greater reduction in hemorrhagic stroke and major bleeding compared with men, with similar efficacy, researchers reported.
    “The principal findings of this secondary analysis... were that the magnitude of reduction in multiple serious bleeding endpoints with a higher-dose edoxaban regimen vs. warfarin, including intracranial hemorrhage, fatal or life-threatening bleeding, and the composite of clinically relevant major or nonmajor bleeding, were greater in women than in men,”
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  • Women may have better survival than men in Merkle cell carcinoma

    9 days ago - By Healio

    Mortality associated with Merkle cell carcinoma may be lower among women compared with men, according to a retrospective study.
    “Studies have observed that women have better outcomes than men in melanoma, but less is known about the influence of sex differences on outcomes for other aggressive cutaneous malignancies,” Moses Tam, MD, of the department of radiation oncology at New York University Langone Health, and colleagues wrote.
    Tam and colleagues culled patients with nonmetastatic Merkle cell carcinoma undergoing surgery and lymph node evaluation from the National Cancer
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