• Trial to assess novel targeted therapy for rare form of kidney cancer

    2 monthes ago - By Healio

    A preclinical study that yielded new insights into a rare pediatric malignancy laid the foundation for a phase 2 trial that is evaluating a novel treatment approach in a specific type of kidney cancer.
    Investigators at The University of Texas MD Anderson Cancer Center developed a mouse model of malignant rhabdoid tumors, an aggressive childhood malignancy that is caused by mutations in the SMARCB1 gene and often starts in the kidneys.
    Researchers determined that blocking proteasome degradation and autophagy - two mechanisms important for clearing protein waste - led to complete
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  • Scientists present a new approach to fight cancer

    2 monthes ago - By News Medical

    In recent years, it's become clear that RNA-binding proteins play a major role in cancer growth. These proteins, active in all cells but especially so in cancer cells, bind to RNA molecules and accelerate cancer cell growth.
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  • Precise decoding of breast cancer cells creates new option for treatment

    2 monthes ago - By ScienceDaily

    Researchers have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They've found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful for a specific group of breast cancer patients.
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