• Genetic mutations of appendix cancer identified, may impact treatment

    8 monthes ago - By ScienceDaily

    To understand why some patients with appendix cancer respond to standard treatment while others do not, researchers performed genetic profiling on 703 appendiceal tumors - the largest such study of this disease to date - to compare mutations present in both cancer types.
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  • MUC16 mutation associated with better gastric cancer survival

    8 monthes ago - By Healio

    Patients with gastric cancer and MUC16-mutant tumors had longer median OS than patients with wild-type MUC16, according to study results published in JAMA Oncology.
    “MUC16 mutations appear to be associated with tumor mutation load and can be used to stratify patients with gastric cancer into prognostically distinct groups. ...This finding may have implications for prognostic prediction and therapeutic guidance for gastric cancer,” Xiangchun Li, PhD, of Tianjin Medical University Cancer Institute and Hospital, and colleagues wrote.
    Gastric cancer is genomically heterogeneous, with
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