• Monoclonal antibody therapy achieves modest reduction in recurrence for patients with HER2-positive DCIS

    1 month ago - By News Medical

    The addition of the monoclonal antibody therapy Trastuzumab to radiotherapy did not reach the protocol objective of a 36% reduction in the ipsilateral breast tumor recurrence rate for women with HER2-positive ductal carcinoma in situ on the NRG Oncology clinical trial NSABP B-43.
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  • Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

    1 month ago - By News Medical

    The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
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