• Multibiomarker disease activity test 'stronger predictor' of radiographic progression in RA

    2 days ago - By Healio

    The adjusted multibiomarker disease activity test for rheumatoid arthritis is prognostic for radio progression, and is a stronger predictor than conventional risk factors, according to data published in Arthritis Research & Therapy.
    “The multibiomarker disease activity blood test measures 12 serum biomarkers, including CRP, to generate a score on a scale of 1-100 that represents the level of disease activity in adult patients with RA,” Jeffrey R. Curtis, MD, MS, MPH, of the University of Alabama at Birmingham, and colleagues wrote. “The MBDA score has categories of
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  • Polygenic risk score alone not superior to known risk factors for identifying depression

    3 days ago - By Healio

    Current polygenic risk scores for depression were not more likely to be linked to major depressive disorder than were other known risk factors, according to results of a case-cohort study published in JAMA Psychiatry.
    However, in conjunction with other risk factors, they may be helpful in identifying risk, researchers noted.
    “Genetics are, in many ways, exactly like any other risk factors - a high genetic liability does not mean doom, but it merely increases risk,” Esben Agerbo, DrMedSc, of the Centre for Integrated Register-based Research and National Centre for
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