• Aromatase inhibitor therapy slows bone age advancement in congenital adrenal hyperplasia

    4 monthes ago - By Healio

    The aromatase inhibitor anastrozole effectively slowed bone age advancement in children with congenital adrenal hyperplasia during 5 years of treatment without changes in bone mineral density or body composition, suggesting the therapy could serve as a useful add-on therapy to glucocorticoid replacement, according to findings published in Clinical Endocrinology.
    “Our study found that bone age maturation slowed in children with congenital adrenal hyperplasia treated with anastrozole,” Kyriakie Sarafoglou, MD, associate professor and director of the Center for Congenital
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