• Identification of Key Genes in Cleft Lip with or without Cleft Palate Regulated by miR-199a-5p

    4 monthes ago - By International Journal of Pediatric Otorhinolaryngology

    Cleft lip with or without cleft palate is one of the most common congenital defects, which etiology involves both genetic and environmental factors. Previous studies have shown that miR-199a-5p may mediate the occurrence of CL/P. However, the key target genes regulated by miR-199a-5p are not clear. In this study, we employed a systematic bioinformatics analysis of target genes regulated by miR-199a-5p which may be involved in CL/P.
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  • Study reveals new genetic causes of non-syndromic cleft lip and palate

    4 monthes ago - By News Medical

    A study conducted by an international research team, which included investigators from Seattle Children's Research Institute, implicates variants in four genes as a primary cause of non-syndromic cleft lip and palate in humans.
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