• Osteonecrosis of Knee and Tibia

    2 monthes ago - By The Journal of Pediatrics

    A 14-year-old boy presented with bilateral knee pain. He had acute lymphoblastic leukemia, B precursor, and had received chemotherapy for 2 years. Following induction and consolidation therapy, maintenance therapy with methotrexate, mercaptopurine, dexamethasone, and vincristine was given. The patient complained of bilateral knee pain in week 103 of maintenance therapy. Physical examination yielded unremarkable findings, and an radiographs showed intact bony structures. Magnetic resonance imaging showed bone infarction with a “map”-like appearance of bilateral femurs and tibias (Figures 1...
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