• Functional Outcomes at 1 Year After PICU Discharge in Critically Ill Children With Severe Sepsis

    1 month ago - By Pediatric Critical Care Medicine

    Objectives:
    To evaluate the functional outcomes in critically ill children with severe sepsis using the Pediatric Overall Performance Category scale and Pediatric Cerebral Performance Category scale and to evaluate the risk factors for “worse outcomes.”
    Design:
    Prospective observational cohort study.
    Setting:
    Tertiary care PICU from September 2017 to October 2019.
    Patients:
    One hundred twenty-one children with severe sepsis, 2 months to 17 years old, admitted to PICU.
    Interventions:
    None.
    Measurements and Main Results:
    Pediatric Overall Performance Category and Pediatric Cerebral...
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  • Long-Term Outcome of PICU Patients Discharged With New, Functional Status Morbidity

    Long-Term Outcome of PICU Patients Discharged With New, Functional Status Morbidity

    1 month ago - By Pediatric Critical Care Medicine

    Objectives:
    To determine the long-term functional status of PICU patients with significant new functional morbidities at hospital discharge.
    Design:
    Longitudinal cohort followed-up using structured chart reviews of electronic health records.
    Setting:
    Electronic health records of former PICU patients at seven sites.
    Patients:
    Randomly selected patients from the Trichotomous Outcome Prediction in Critical Care study discharged from the hospital with new functional status morbidity who had sufficient electronic health record data to determine functional...
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  • Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation*

    Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation*

    1 month ago - By Pediatric Critical Care Medicine

    Objectives:
    The Life After Pediatric Sepsis Evaluation investigation recently reported that one-third of children who survive sepsis experience significant health-related quality-of-life impairment compared with baseline at 1 year after hospitalization. Pediatric Sepsis Biomarker Risk Model is a multibiomarker tool for estimating baseline risk of mortality among children with septic shock. We determined if the Pediatric Sepsis Biomarker Risk Model biomarkers have predictive capacity for estimating the risk of hospital mortality and long-term health-related quality-of-life morbidity among...
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