• Renal Replacement Therapy in the Critically Ill Child*

    9 monthes ago - By Pediatric Critical Care Medicine

    Objectives:
    Although renal replacement therapy is widely used in critically ill children, there have been few comprehensive population-based studies of its use. This article describes renal replacement therapy use, and associated outcomes, in critically ill children across the United Kingdom in the largest cohort study of this patient group.
    Design:
    A retrospective observational study using prospectively collected data.
    Setting:
    Data from the Pediatric Intensive Care Audit Network database which collects data on all children admitted to U.K. PICUs.
    Patients:
    Children (
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  • The Effect of Acetaminophen on Temperature in Critically Ill Children: A Retrospective Analysis of Over 50,000 Doses

    The Effect of Acetaminophen on Temperature in Critically Ill Children: A Retrospective Analysis of Over 50,000 Doses

    9 monthes ago - By Pediatric Critical Care Medicine

    Objectives:
    Acetaminophen is widely used in PICUs. Although randomized controlled trials suggest that acetaminophen significantly reduces body temperature in adults, the effect of acetaminophen on temperature in critically ill children has not been previously quantified.
    Design:
    Retrospective observational cohort study.
    Setting:
    Single-center general and cardiac PICU in a specialist children's hospital.
    Patients:
    All children who received acetaminophen or had a fever while on the ICU over a 40-month period .
    Interventions:
    None.
    Measurements and Main Results:
    In total, 58,177 doses of...
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