Sorafenib improves PFS in refractory desmoid tumors
29 days ago - By Healio
Patients with progressive, refractory or symptomatic desmoid tumors derived a significant PFS benefit from sorafenib, according to results of a double-blind, placebo-controlled randomized phase 3 study published in The New England Journal of Medicine.
Sorafenib also included durable responses in this patient population, results showed. “In a retrospective analysis, sorafenib, an oral multitargeted receptor tyrosine kinase inhibitor, at a starting dose of 400 mg once daily was shown to have acceptable safety and was associated with a response rate of
Read more ...
Dupilumab significantly improves asthma control
29 days ago - By Healio
Patients with uncontrolled, moderate-to-severe asthma treated with dupilumab demonstrated significant improvement in asthma control regardless of exacerbation history, according to data presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting.
“Dupilumab, a fully human anti-interleukin -4 receptor a monoclonal antibody, inhibiting IL-4/IL-13 signaling pathways, key drivers of type 2 inflammation, is approved for treatment of adults with inadequately controlled moderate-to-severe atopic dermatitis,” Jonathan Corren, MD, from David Geffen
Read more ...
The headlines of Master Doctor
These '10 Year Challenge' Climate Change Photos Are Absolutely Haunting
These before and after photos proving climate change is definitely happening are devastating The “10 year challenge” has been sweeping social media with people posting pics of...
Raising A Child With Strong Faith When You're Not So Sure
I was making dinner one night when my 3-year-old came up to me with a stack of papers in his hands. He hands me the papers and says “These are to teach you about Jesus. Share...
A National Survey on Interhospital Transport of Children in Cardiac Arrest*
Objectives: To describe the U.S. experience with interhospital transport of children in cardiac arrest undergoing cardiopulmonary resuscitation. Design: Self-administered...
Does breastfeeding REALLY make you lose weight?
Of all the touted benefits of breastfeeding , the idea that I would effortlessly lose all of the baby weight was a major motivator for me. Unfortunately, in my case, it turned...
Opioids linked to birth defect of babies born with intestines hanging...
Roughly 1,800 such cases are seen in the US each year, but the number has been rising and officials don't know why. Now, the CDC believes there could be a link with opioids...
The Flu Poses Serious Risks To Pregnant Women And Their Babies
The flu is much more than just a bad cold. Hundreds of thousands of people are hospitalized each year due to the flu, and last year alone, 79,400 deaths were attributed to...
Obesity means 'generation of children may live shorter lives than their parents'
The Welsh Government has launched a consultation on its first ever obesity strategy
A Quarter of Antibiotics Prescribed for Children and Adults Found Unnecessary
One in seven privately insured children and non-elderly adults among the study cohort received antibiotics for cases that were not justified medically, according to new research.
Overprescription of Opioids for Elbow Fractures in Children: CHOP Surgeons
Patients only took less than 5 percent of the prescribed amount, and one in five did not receive any opioid medication to manage pain which could lead to opioid diversion.
Gay Fathers and Their Children Still Structurally Stigmatized: Study
Gay fathers and their children continue to experience stigma with potentially harmful physical and psychological effects.