• Demonstration of Technical Feasibility and Viability of Whole Eye Transplantation in a Rodent Model

    5 monthes ago - By Journal of Plastic, Reconstructive & Aesthetic Surgery

    : Whole eye transplantation holds promise for vision restoration in devastating/disabling visual loss not amenable to surgical or neuroprosthetic treatment options. The eye includes multiple tissues with distinct embryonic lineage and differential antigenicity. Anatomically and immunologically, the eye is unique due to its avascular and highly vascular components. Our goal was to establish technical feasibility, demonstrate graft viability and evaluate histologic changes in ocular tissues/adnexae in a novel experimental model of WET that included globe, adnexal, optic nerve and periorbital...
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