• Response to letter commenting on the use of blue dye in sentinel lymph node biopsy

    6 monthes ago - By Journal of Plastic, Reconstructive & Aesthetic Surgery

    We read with interest the reply from Rudman and colleagues1 to our publication2 but disagree with their assertion that blue dye must be used to increase the accuracy of sentinel lymph node biopsy for melanoma. In our series, the use of blue dye did not improve the sensitivity of intra-operative sentinel node identification but increased the number of nodes harvested by 5%. Our findings correspond with a meta-analysis performed by Niebling et al in 2016,3 where pooled analysis of 66 studies showed a 99% SLN identification rate using radiocolloid without blue dye.
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  • Response to ‘Sentinel lymph node biopsy in melanoma: which hot nodes should be harvested and is blue dye really necessary?'

    6 monthes ago - By Journal of Plastic, Reconstructive & Aesthetic Surgery

    We read with great interest Ranson et als' recent publication, ‘Sentinel lymph node biopsy in melanoma: which hot nodes should be harvested and is blue dye really necessary?'.1 This article retrospectively analysed 42 nodal basins in which greater than one node had been harvested, comparing the overall sensitivity of their blue dye and radiocolloid procedures with the sensitivity that might have be achieved had, theoretically, cold blue nodes been left in situ. They state that this approach could have resulted in a 5% reduction in the number of nodes harvested with no apparent change in...
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